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KMID : 1146320220100020068
Journal of Health Technology Assessment
2022 Volume.10 No. 2 p.68 ~ p.74
Analyses of Prescription Patterns of Antidepressants Among Psoriasis Patients in South Korea Using HIRA-NPS Data Set
Han Mi-Yeon

Lee Eui-Kyung
Abstract
Objectives: To analyze the demographic characteristics of patients who were prescribed antidepressants after diagnosis of psoriasis and to analyze the prescription patterns of antidepressants that may affect the exacerbation of psoriasis.

Methods: The prescription patterns of patients who were
prescribed antidepressants at least once after diagnosis of psoriasis (ICD-10: L40) were analyzed using data from the Health Insurance Reviews & Assessment Service National Patient Sample (HIRANPS) from 2018 to 2020. For statistical analysis, chi-square test and logistic regression analysis were performed, and all analyses were carried out using SAS 9.4.

Results: In Korean psoriasis patients, the rate of prescription of antidepressants after diagnosis of psoriasis was 7.5% and 25.3% of the prescribed antidepressants were related to exacerbation of psoriasis. In particular, antidepressants
associated with exacerbation of psoriasis were frequently prescribed by female (56.4%), over 60 years of age (40%), and primary care institutions (70.2%).

Conclusion: In psoriasis patients, the prescription rate of antidepressants was higher among female, and correlated with increasing age and decreasing income level. Psycho-dermatological treatment considering the demographic characteristics is needed to manage depressive symptoms, and antidepressants associated with exacerbation of psoriasis need to be prescribed more cautiously.
KEYWORD
Psoriasis, Antidepressants, Health insurance claim data, Prescription patterns, Psychodermatology
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